Calcium as a biased cofactor
نویسندگان
چکیده
منابع مشابه
Calcium ion as a cofactor in Na channel gating.
Calcium ions in the external medium stabilize the resting state of voltage-dependent channels, including Na channels. This effect of calcium on channel gating is usually explained in terms of the surface charge hypothesis, which proposes that local adsorption of calcium ion to the outside of the membrane alters the intramembranous electric field, thus influencing channel behavior indirectly. Ca...
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Contributed equally to this work Present address: Institute of Biochemistry, Splaiul Independentei 296, 060031 Bucharest 17, Romania Present address: Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Address correspondence to: Ineke Braakman, Cellular Protein Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands, Pho...
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ژورنال
عنوان ژورنال: Science
سال: 2020
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.abb4393